Cholesterol Metabolism in Type 1 Diabetes

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Cholesterol metabolism in type 1 diabetes.

Little information is available on cholesterol absorption and synthesis in human type 1 diabetes. We studied these variables using serum cholesterol precursor sterol ratios to cholesterol as surrogate markers of cholesterol synthesis and those of cholestanol and plant sterols to reflect cholesterol absorption in seven type 1 diabetic subjects and in five age- and body weight-matched control sub...

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Cholesterol metabolism in type 2 diabetes

This thesis is based on the following original articles, which are referred to in the text by their Roman numerals. metabolism in non-insulin dependent type 2 diabetics. cholesterol metabolism in obese type 2 diabetes. a new component of the metabolic syndrome: low cholesterol absorption. ABBREVIATIONS ABC adenosine triphosphate-binding cassette transporter ACAT acyl-CoA cholesterol acyltransfe...

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Cholesterol absorption and synthesis in children with type 1 diabetes.

OBJECTIVE The levels of the surrogate markers of cholesterol absorption (cholestanol and plant sterols) and synthesis (cholesterol precursors) in serum have suggested that in adult type 1 diabetes, cholesterol absorption is high and synthesis is low compared with type 2 diabetic or control subjects. Accordingly, these findings were further studied in children with type 1 diabetes. RESEARCH DE...

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Abnormalities of cholesterol metabolism in diabetes.

The basic lesion leading to the high morbidity and mortality in diabetes is atherosclerosis. The histological picture of atherosclerosis in the diabetic is similar to that found in the non-diabetic, yet atherosclerosis is more frequent and more severe in diabetes (West, 1978; Krolewski et al. 1987a,h). Gangrene of the foot is five times more common and myocardial infarction and strokes are also...

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Metabolic effects of fasting in adolescents with diabetes type 1

Type I diabetes mellitus is a common chronic disease in adolescents. According to statistics, 12,243 diabetic Muslims fast in thirteen Islamic countries, 43% of whom have type I diabetes. This longitudinal study was conducted on volunteer adolescents with type I diabetes aged 13-18 years for 15 days using the census method. Three days before Ramadan and during the last three days of the study p...

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ژورنال

عنوان ژورنال: Diabetes

سال: 2004

ISSN: 0012-1797,1939-327X

DOI: 10.2337/diabetes.53.9.2217